The Hormone Behind Ozempic, Found in a Spoonful of Olive Oil

Editorial still-life of a glass bottle of golden olive oil with a dropper, whole olives, and a sprig of olive branch, styled on cream and stone surfaces in Oliiv's dark olive, lime, and off-white palette

A new study made headlines this week for an unexpected reason: scientists found that a small amount of olive oil, taken before a sugary drink, appeared to trigger the same gut hormones targeted by GLP-1 weight-loss drugs. The research, published in the American Diabetes Association's journal Diabetes and reported on by Newsweek, found that olive oil slowed gastric emptying and increased secretion of GLP-1 and GIP — the very incretin hormones that drugs like Ozempic are designed to mimic.

It is a mouse study, not a human trial, and the dietitians quoted alongside it were quick to say so. "I would avoid adopting a new health habit just because there is a study that shows a benefit to mice," registered dietitian Lisa Valente told Newsweek. But the finding lands at an interesting moment. Only this week, researchers at Cambridge were asking what the GLP-1 era is quietly leaving out of people's diets: nutrient density, the thing a spoonful of real food can offer that a prescription cannot.

We think that is the more useful story here. Not "olive oil as a drug," but olive oil as evidence that the body already has the tools it needs — if it is given the right raw materials.

The daily ritual

The social-media version of this idea is the olive oil shot: a morning tablespoon, taken neat, often on an empty stomach. We would gently steer you elsewhere. A shot treats olive oil like a supplement to be endured. A ritual treats it like what it actually is — a fresh, living food, closer to pressed fruit juice than to a bottle on a shelf.

Valente's own advice points the same way: skip the shot, and let olive oil do its work where it already belongs — dressing a salad, finishing a plate of vegetables, replacing the butter in a pan. "A heart-healthy salad dressing may be a great way to start," she notes. That is a ritual, not a stunt: the same small act, repeated daily, until it is simply how you eat.

This is the frame Oliiv has always worked from. One spoonful, each morning, of oil that is still early in its life. Not a trend to try for a week, but a quiet addition to how the day begins.

Why it holds up scientifically

Set the mouse study aside for a moment, because olive oil's case does not rest on it. The evidence that matters most comes from decades of human research, and it keeps pointing the same way.

  • A 28-year study of nearly 90,000 US health professionals, reviewed by the British Heart Foundation, found that the highest olive oil intake was linked to a 19% lower risk of dying from cardiovascular causes, with benefit visible from as little as half a tablespoon a day.
  • In the US, the American Heart Association has reported comparable findings: people who replaced margarine, butter, mayonnaise or dairy fat with olive oil saw a measurably lower risk of heart disease.
  • In the EU, regulators have gone further than "may help." Following a formal scientific opinion from EFSA, olive oil polyphenols carry an authorised health claim: they contribute to the protection of blood lipids from oxidative stress, at a threshold of around 5mg of hydroxytyrosol a day — roughly two tablespoons of a genuinely polyphenol-rich oil.

That last point matters more than it first appears. Not every olive oil clears that polyphenol threshold. Refined, late-harvest, or long-stored oils lose their bioactive compounds well before the bottle is empty. The EFSA claim is, in effect, a quiet argument for freshness.

Rooted in provenance

This is where the harvest date earns its place on the label rather than the shelf. Polyphenols begin fading from the moment an olive is pressed, so an oil's power to support the body is highest in its first months and declines steadily after. A bottle with no date, or a date from last year, is very unlikely to deliver the levels EFSA's panel assessed. Oliiv is cold-pressed within hours of harvest from single-estate groves farmed regeneratively, early in the season, when polyphenol content is at its peak. The date on the bottle is not decoration. It is the number that determines whether the ritual actually does anything.

A simple decision, made daily

None of this requires a shot, a trend, or a headline about mice. It requires a spoonful of fresh, harvest-dated, properly pressed olive oil, taken the same way, most days — on vegetables, in a dressing, over something simple at the end of cooking rather than the start.

The appeal of a drug that mimics GLP-1 is that it does the work for you. The appeal of olive oil, used well, is almost the opposite: it asks for nothing more than a small, repeatable habit, built around a food that has been nourishing people in the Mediterranean for millennia. That is the ritual we would rather you keep.

Sources: Newsweek, "People Are Taking Olive Oil Shots" (2026), reporting on a mouse study published in Diabetes (American Diabetes Association); British Heart Foundation, "Olive oil and living longer"; American Heart Association, "Olive oil may lower heart disease risk"; European Food Safety Authority, Scientific Opinion on olive oil polyphenols (EFSA Journal 2011;9(4):2033).